Simple Daily Habits to Lower Low-Grade Inflammation

Low-grade inflammation is like an invisible fire smoldering inside the body. Unlike the obvious swelling you might get from a sprained ankle, this type of inflammation doesn’t cause immediate pain or redness—but it quietly wears down your health over time. Many women in their 30s, 40s, and 50s struggle with fatigue, brain fog, joint stiffness, bloating, or stubborn weight gain—often chalking it up to aging, stress, or a busy lifestyle—without realizing that chronic, low-grade inflammation could be at the root.
Experiencing low energy, frequent headaches, or muscle soreness without exercise? These might seem like everyday annoyances, but they can be signs of inflammation flying under the radar.
The good news? Low-grade inflammation treatment doesn’t require extreme diets or complicated health routines. With simple, science-backed habits, you can naturally lower inflammation, improve energy levels, and support long-term well-being.
What Is Inflammation in the Body?
Inflammation is the body’s natural defense system, helping to heal injuries and fight infections. When you cut yourself or catch a cold, inflammation kicks in to help you recover—that’s healthy and necessary.
But when inflammation lingers at a low-grade, chronic level, it stops being protective and starts becoming harmful. This type of inflammation is subtle—it won’t cause a fever or visible swelling, but it can quietly disrupt your metabolism, hormones, and immune system.
Types of Inflammation:
- Acute Inflammation: Short-term, beneficial, and necessary for healing (e.g., swelling after a cut, redness around an injury, or a fever when fighting an infection).
- Chronic Low-Grade Inflammation: Persistent, subtle, and often unnoticed. This long-term immune activation can contribute to:
- Heart disease
- Insulin resistance
- Autoimmune disorders
- Early cognitive decline
- Mood swings and low energy
- Increased belly fat and weight gain related to inflammation
Research suggests that conditions like low-grade inflammation obesity, PCOS, and metabolic syndrome are interconnected, making chronic inflammation a key factor in many modern health concerns.
Symptoms of Low-Grade Inflammation
One of the most challenging aspects of low-grade inflammatory changes is how they creep in with everyday symptoms that seem unrelated—or easy to ignore.
Have you ever thought, “Why am I always tired?”, “Why can’t I focus?”, or “Why do my joints ache when I didn’t even work out?” These are often dismissed as stress or aging but could be symptoms of chronic low-grade inflammation.
Common symptoms of low-grade inflammation include:
- Fatigue that doesn’t improve with rest (fatigue and inflammation)
- Unexplained brain fog or difficulty concentrating (brain fog causes)
- Mild joint aches or stiffness, even without injury (joint stiffness causes)
- Digestive discomfort, bloating, or irregular bowel movements (digestive inflammation symptoms)
- Stubborn weight gain, especially around the midsection (weight gain inflammation)
- Skin issues like acne, eczema, or redness that flare up unpredictably (skin inflammation symptoms)
- Mood swings, anxiety, or low mood (inflammation and mood swings)
- Frequent headaches without a clear cause (inflammation-related headaches)
- Muscle soreness without exercise or clear strain (muscle soreness causes beyond exercise)
- Low energy that doesn’t improve with caffeine or extra sleep (low energy causes)
If you’re nodding along to any of these, you’re not alone—and you don’t have to just “deal with it”. These symptoms of chronic low-grade inflammation are your body’s way of signaling that something needs attention.
What Causes Low-Grade Inflammation?
There’s rarely a single culprit behind chronic inflammation—it’s usually a combination of lifestyle choices, environmental factors, and underlying health conditions. The tricky part? Many of these triggers are woven into everyday life.
Major contributors to chronic inflammation:
1. Diet High in Processed Foods
- Ultra-processed snacks, sugary drinks, and refined carbs spike blood sugar, leading to blood sugar crashes that trigger inflammation.
- Highly processed foods can also disrupt gut bacteria, causing digestive inflammation symptoms like bloating and gas.
2. Chronic Stress & Poor Sleep
- Long-term stress raises cortisol, which, when elevated for too long, fuels inflammation.
- Sleep deprivation (less than 6 hours per night) increases inflammatory markers like CRP and can worsen fatigue and mood swings.
3. Excess Body Fat
- Adipose (fat) tissue, particularly around the abdomen, releases inflammatory molecules, making low-grade inflammation obesity a significant risk factor.
- This is why belly fat isn’t just a cosmetic concern—it’s an inflammation driver.
4. Hormonal Imbalances & Insulin Resistance
- Conditions like PCOS, metabolic syndrome, and prediabetes often come with elevated inflammatory markers.
- Hormonal shifts, especially during perimenopause, can increase inflammation and contribute to weight gain.
5. Sedentary Lifestyle
- Sitting for long periods slows lymphatic drainage and reduces circulation, making it harder for the body to clear out inflammatory waste.
- Even regular exercisers aren’t immune if they’re sedentary for the rest of the day.
When these factors pile up, they create the perfect storm for chronic low-grade inflammation, leaving you feeling “off” without a clear explanation.
How to Reduce Inflammation in the Body
Here’s the good news: Low-grade inflammation treatment doesn’t require radical changes. It’s about sustainable daily habits that gently calm inflammation and support overall health. Start small—consistency beats perfection every time.
1. Eat to Lower Inflammation
What you eat can either fuel inflammation or fight it. An anti-inflammatory diet doesn’t mean giving up everything you love—it’s about adding more of the good stuff and being mindful of triggers.
Anti-Inflammatory Foods to Focus On:
- Colorful vegetables and fruits: Rich in antioxidants that neutralize inflammation. Think berries, leafy greens, and cruciferous veggies like broccoli.
- Healthy fats: Foods like salmon, walnuts, chia seeds, and flaxseeds help balance pro-inflammatory omega-6 fats.
- Herbs and spices: Turmeric (curcumin), ginger, and garlic have powerful anti-inflammatory compounds.
- Fermented foods: Yogurt, kefir, sauerkraut, and kimchi support gut health, helping to reduce digestive inflammation symptoms like bloating.
Foods to Minimize:
- Ultra-processed snacks and refined sugars: They spike insulin and trigger inflammatory pathways.
- Highly processed vegetable oils: Found in many packaged foods, these are rich in omega-6 fats that can worsen inflammation.
- Artificial sweeteners and additives: Linked to gut microbiome imbalances and increased inflammation.
Simple tip: Swap sugary drinks for herbal teas or water infused with lemon and berries. Add turmeric to soups or sprinkle chia seeds onto yogurt for an anti-inflammatory boost.
2. Move Your Body (Without Overdoing It)
Movement is one of the most effective ways to lower inflammation—but the key is consistency, not intensity. Overexercising can actually spike inflammatory markers, so focus on moderate, enjoyable activities.
Best types of movement for inflammation reduction:
- Walking: Just 30 minutes a day can significantly lower inflammation markers like CRP (PubMed Study).
- Strength training: Builds muscle mass and reduces inflammation linked to insulin resistance and belly fat.
- Gentle yoga and stretching: Combines movement with breathwork, helping to calm inflammation driven by chronic stress.
For women dealing with low-grade inflammation PCOS or hormonal imbalances, balance is crucial—think strength training combined with restorative movement.
3. Manage Stress Like Your Health Depends on It (Because It Does)
Stress isn’t just mental—it’s physical. Chronic stress keeps the body in a constant low-grade inflammatory state, contributing to fatigue, mood swings, and brain fog.
Simple stress-reducing habits:
- Deep breathing exercises: Just 5 minutes a day can lower cortisol and reduce inflammation.
- Journaling or gratitude practice: Shifts your focus away from stressors, calming the body’s stress response.
- Daily nature exposure: Even a 10-minute walk outdoors can lower inflammation biomarkers and boost mood.
4. Prioritize Restorative Sleep
Sleep is when your body repairs itself—and without enough of it, inflammation thrives. Studies show that getting less than six hours of sleep per night raises CRP levels and worsens symptoms like brain fog, weight gain, and low energy.
Better sleep strategies for inflammation control:
- Keep a consistent sleep schedule, even on weekends.
- Limit screen time at least an hour before bed to avoid blue light disrupting melatonin production.
- Create a cool, dark, and quiet sleep environment to promote deeper rest.
Even small improvements in sleep can significantly lower inflammation and improve energy levels during the day.
How Do You Fix Low-Grade Inflammation With Targeted Supplements?
While lifestyle habits—such as an anti-inflammatory diet, stress management, and regular movement—are the cornerstone of managing low-grade inflammation, targeted supplements can provide an extra layer of support. By complementing consistent healthful habits, the right nutrients can help calm inflammatory pathways, boost energy levels, and alleviate lingering symptoms like brain fog, muscle aches, or digestive discomfort.
Supplements aren’t magic bullets, but they can help break through plateaus, especially for women in their 30s to 50s. In many cases, adding carefully chosen anti-inflammatory supplements offers a significant boost in vitality and wellbeing.
Below is a list of science-backed supplements that target chronic inflammation. Each is selected for its potential to address inflammation symptoms that often show up as bloating, unexplained weight gain, muscle soreness without a clear cause, or persistent fatigue. Keep in mind that the best outcomes come from a holistic approach—combining supplementation with daily practices that reduce your overall inflammatory load.
Disclaimer: Always consult your healthcare practitioner or a registered dietitian before beginning any supplement regimen, especially if you have underlying health conditions or take other medications.
Top Supplement Recommendations for Low-Grade Inflammation Treatment
1. Curcumin (Turmeric Extract)
Curcumin, the active compound in turmeric, is one of the most well-researched natural anti-inflammatories. It works by blocking inflammatory molecules like NF-κB and cytokines that fuel chronic inflammation.
Why it’s effective:
- Reduces joint inflammation and stiffness, which is ideal if you experience morning aches or unexplained joint pain.
- Can improve brain fog and enhance cognitive clarity.
- Shown to lower inflammation markers like CRP in people with metabolic syndrome and arthritis (PubMed Study).
Tip: Curcumin is poorly absorbed on its own. Look for supplements containing piperine (black pepper extract) or specialized absorption technologies.
One option to consider is the Doctor’s Best High Absorption Curcumin with C3 Complex & BioPerine (500 mg), which is formulated for improved bioavailability.
Recommended dose: 500–1,000 mg of standardized curcumin extract daily, divided with meals.
2. Omega-3 Fatty Acids (Fish Oil or Algae-Based Alternatives)
Omega-3 fatty acids, especially EPA and DHA, help counteract the pro-inflammatory effects of excessive omega-6 fats common in modern diets. These essential fats are crucial for reducing systemic inflammation.
Why it’s effective:
- Lowers inflammation markers like CRP and IL-6.
- Reduces symptoms like joint stiffness, fatigue, and low mood.
- Beneficial for those with weight gain linked to inflammation or insulin resistance.
Food source tip: Eat fatty fish (salmon, sardines, mackerel) twice a week, or take high-quality fish oil supplements if that’s challenging.
High-quality fish oil options include:
- THORNE Advanced DHA (650 mg DHA and 200 mg EPA): Supports brain health, heart function, and overall inflammation management.
- NOW Foods DHA-500 with 250 mg EPA: Known for supporting brain and cardiovascular health.
For plant-based options:
- Nordic Naturals Algae DHA (500 mg): A vegan-friendly source of DHA, ideal for supporting brain, eye, and nervous system function.
- Vegan Vitality Omega-3: Plant-based and designed for joint, heart, and immune support without the fishy aftertaste.
Recommended dose: 1,000–3,000 mg combined EPA and DHA daily.
3. Boswellia serrata (Frankincense Extract)
Used for centuries in traditional medicine, Boswellia is now recognized in modern research for its anti-inflammatory properties. It inhibits 5-lipoxygenase, an enzyme that contributes to inflammation.
Why it’s effective:
- Eases joint discomfort and improves mobility, particularly for osteoarthritis sufferers.
- Helps with gut inflammation, reducing bloating and digestive discomfort.
- Supports overall reduction in chronic low-grade inflammation symptoms.
High-quality options to consider:
- NOW Boswellia Serrata Extract (500 mg, 200 Softgels): Softgels with standardized Boswellia extract in an MCT oil base for better absorption.
- Bulk Supplements Boswellia Serrata Extract Powder (500 mg per serving): Pure powder form for customizable dosing and easy mixing into beverages.
Recommended dose: 300–500 mg of standardized extract, taken 2–3 times daily with food.
4. Vitamin D
Vitamin D deficiency is common, especially for those working indoors or living in less sunny regions. Low levels are associated with higher inflammation and weakened immune function.
Why it’s effective:
- Modulates immune response, reducing chronic inflammation.
- Helps improve low energy and mood swings often linked to inflammation.
- Can lower inflammation markers like CRP.
Tip: Test your vitamin D levels before supplementing. Aim for optimal, not excessive, doses.
For high-quality supplementation, consider:
- Pure Encapsulations Vitamin D3 (5,000 IU): A clean, allergen-free formula supporting bone, immune, and cardiovascular health.
Recommended dose: 1,000–2,000 IU daily, or as directed by your healthcare provider.
5. Probiotics for Gut Health
Your gut is a critical player in regulating inflammation. An imbalanced gut microbiome can contribute to bloating, brain fog, and skin inflammation symptoms like acne or eczema.
Why it’s effective:
- Supports gut barrier function, preventing inflammatory substances from leaking into the bloodstream.
- Reduces digestive inflammation symptoms and improves nutrient absorption.
- May ease inflammation-related skin flare-ups.
Food-first approach: Include fermented foods like yogurt, kefir, kimchi, and sauerkraut.
For supplemental support:
- NOW Foods Probiotic-10™ (25 Billion CFUs): Offers a variety of clinically validated probiotic strains for comprehensive gut health.
- Saccharomyces 10B (Saccharomyces boulardii): A targeted probiotic known for supporting gut flora balance, particularly useful for those dealing with digestive inflammation and antibiotic-related gut issues.
Recommended dose: Probiotic supplements with diverse strains and at least 10–20 billion CFUs.
What Does It Mean When Your Blood Test Shows Inflammation?
Hearing that your blood work shows inflammation can be unsettling—but understanding what those markers mean helps you take proactive steps.
Common inflammatory markers:
- C-reactive protein (CRP): Elevated levels indicate inflammation somewhere in the body.
- Erythrocyte sedimentation rate (ESR): Measures general inflammation but doesn’t pinpoint the cause.
- Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-α): Cytokines involved in chronic inflammation.
Why your blood test might show inflammation:
- Chronic stress or poor sleep habits
- High consumption of processed foods and sugar
- Sedentary lifestyle with limited movement
- Underlying conditions like PCOS, autoimmune diseases, or metabolic syndrome
- Excess body fat, particularly around the midsection (low-grade inflammation obesity)
Elevated inflammation markers don’t automatically mean you have a severe condition—but they’re a sign to investigate further. Work with your healthcare provider to identify potential triggers and develop a low-grade inflammation treatment plan tailored to your needs.
Putting It All Together
Chronic, low-grade inflammation is more common than you might think—but it doesn’t have to define your health. With consistent habits and targeted strategies, you can calm the inflammation and start feeling more like yourself again.
Quick recap for effective low-grade inflammation treatment:
- Prioritize whole foods: Load up on fruits, veggies, healthy fats, and fermented foods.
- Move daily: Gentle walks, yoga, and strength training lower inflammation while improving mood and energy.
- Manage stress: Simple practices like deep breathing, journaling, and nature time can lower cortisol and inflammation.
- Improve sleep quality: Aim for 7–9 hours of restful sleep to support your body’s repair processes.
- Consider key supplements: Curcumin, omega-3s, Boswellia, vitamin D, and probiotics can enhance your efforts.
- Monitor your markers: Regular blood work helps track progress and fine-tune your approach.
Final Thoughts
If you’re tired of feeling run-down, battling unexplained aches, or dealing with stubborn bloating and brain fog, it’s time to take action. Chronic inflammation may be silent, but your body’s subtle signals shouldn’t be ignored.
If you want practical, science-backed ways to support your health and stay ahead of chronic inflammation, subscribe to my weekly newsletter. I share easy-to-implement tips that fit into your everyday life—because taking care of yourself doesn’t need to be complicated.
References
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Calder, P. C. (2015). Marine omega-3 fatty acids and inflammatory processes: Effects, mechanisms and clinical relevance. Biochimica et Biophysica Acta (BBA) – Molecular and Cell Biology of Lipids, 1851(4), 469–484.
Daily, J. W., et al. (2016). Efficacy of turmeric extracts and curcumin for alleviating the symptoms of joint arthritis: A systematic review and meta-analysis of randomized clinical trials. Journal of Medicinal Food, 19(8), 717–729.
Furman, D., et al. (2019). Chronic inflammation in the etiology of disease across the life span. Nature Medicine, 25, 1822–1832.
Hill, C., et al. (2014). Expert consensus document: The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nature Reviews Gastroenterology & Hepatology, 11(8), 506–514.
Hotamisligil, G. S. (2006). Inflammation and metabolic disorders. Nature, 444(7121), 860–867.
Irwin, M. R. (2019). Sleep and inflammation: Partners in sickness and in health. Nature Reviews Immunology, 19(11), 702–715.
Koh, K. K., et al. (2005). Inflammatory markers and the metabolic syndrome. Journal of the American College of Cardiology, 46(11), 1978–1985.
Robinson, P. C., et al. (2016). Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis. Nature Reviews Rheumatology, 12(10), 580–592.
Ulbricht, C., et al. (2011). Boswellia serrata: An evidence-based systematic review by the Natural Standard Research Collaboration. Journal of Dietary Supplements, 8(1), 45–65.
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Who is Shawn Wells?
Although I’ve suffered from countless issues, including chronic pain, auto-immunity, and depression, those are the very struggles that have led me to becoming a biochemist, formulation scientist, dietitian, and sports nutritionist who is now thriving. My personal experiences, experiments, and trials also have a much deeper purpose: To serve you, educate you, and ultimately help you optimize your health and longevity, reduce pain, and live your best life.
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