Spermidine’s Health and Anti-aging Benefits

Can we reverse our age?

I’m not talking about a fountain of youth and I’m not just talking about the usual ways of taking care of ourselves that include working out and eating well. I’m asking could be a particular ingredient or supplement that can help.

Spermidine may be the answer to this.

But what is it? Despite the odd name, spermidine has remarkable benefits to health and longevity. It is a naturally occurring organic compound found in foods such as whole grains, dairy, beans, fish and vegetables. It’s also produced by the human body which is why it should come as no surprise that there are many health benefits of spermidine.

The benefits of spermidine include anti-aging properties, brain function, heart health, the improvement of your immune system and the ability to strengthen your bones among others.

Spermidine is a natural polyamine that exists in our cells and has the power to counteract aging. It takes hacking your age to the next level. It’s the newest biohack for longevity.

Along with the amazing properties for longevity, spermidine is highly antioxidant and inflammation-reducing. It also regulates cell growth, proliferation and death.

But that’s not all it can do. There are actually many benefits spermidine can provide.

It’s good for your skin.

Spermidine is good for your skin. It helps to reduce wrinkles and fine lines, improve the elasticity of the skin, improve skin tone and texture, help to reduce acne and improve hydration.

You may also notice a reduction in roughness as you age!

It protects your brain.

Spermidine may help protect your brain from the effects of aging and prevent brain damage caused by stroke, Alzheimer’s disease and other neurological disorders, particularly through autophagy. In addition to helping you stay sharp as you get older, spermidine may also prevent memory loss and cognitive decline.

It’s thought that spermidine works by increasing the activity of an enzyme called PARP1, which helps repair damaged DNA inside cells. Studies show that spermidine can also reduce inflammation in the body—a factor linked to many diseases—and improve insulin resistance (a precursor to diabetes).

It supports mitochondria

Your mitochondria are the powerhouse of your cells. They are where your body gets energy. By making them stronger and optimizing your mitochondria, you will not only have more energy but you will become essentially younger.

There was a recent study that found spermidine turns on mitochondrial biogenesis. This is the process by which your body’s cells increase mitochondrial numbers.(1) The study looked at mitochondria in heart cells and researchers found that spermidine effectively reversed cardiac aging.(2) Another check in the category for longevity!

It improves heart health

Spermidine also seems to be a promising heart disease prevention agent. A recent study shows that spermidine has beneficial effects on health and lifespan in mice, and that these effects are the result of improved cardiovascular function. Similar effects of spermidine on humans are supported by epidemiological studies.(3)

In addition to these promising benefits for heart health, spermidine has been shown to reduce oxidative stress on cells (which are at higher risk for damage during aging). Oxidative stress is associated with chronic inflammation resulting from unhealthy diet choices; this type of inflammation increases your chances of developing conditions such as cancer and diabetes over time if left unchecked.

Conclusion

Spermidine is a nutrient that has many benefits, so it’s worth looking into whether it could help you. It can be especially beneficial for cardiovascular health, brain function and skin health.

As mentioned above, spermidine can be found in some of the common foods we eat but if you are looking to supplement make sure that when choosing a spermidine supplement (or any supplement), you find a company that uses high-quality, clean ingredients backed by verifiable science and that they prioritize and publicize testing on purity, potency and safety.

1. “What Is Mitochondrial Biogenesis? Benefits & Effects.” Neurohacker Collective, https://neurohacker.com/what-is-mitochondrial-biogenesis-benefits-effects.
2. “What Is Mitochondrial Biogenesis? Benefits & Effects.” Neurohacker Collective, https://neurohacker.com/what-is-mitochondrial-biogenesis-benefits-effects.
3. de Cabo, Rafael, and Pácido Navas. “Spermidine to the Rescue for an Aging Heart.” Nature Medicine, U.S. National Library of Medicine, 6 Dec. 2016, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853099/.